Citation:
Casstevens, J.W.,
Cohen D., Newman F.L., & Dumaine, M.. (2006) Evaluation of a Mentored
Self-Help Intervention
for the Management of Psychotic
Symptoms.
International Journal of Psychosocial Rehabilitation.
11
(1),
37-49
AcknowledgementThe
authors would like to acknowledge and thank research assistants Constanza Bade,
Ann J. Galinanes and Danielle Vandenbent for contributing to data entry and data
collection, and the Florida International University Graduate Student
Association for contributing funding.
Contact:W. J. Casstevens
Department of Social
Work
Campus Box 7639
North Carolina State University
Raleigh, NC
27695-7639, USA
AbstractThis pilot study
employs a quasi-experimental pre-post design (n = 27) to evaluate the impact of
a mentored self-help workbook (Coleman & Smith, 1997) intervention.
Participants are diagnosed with severe and persistent mental disorders and
experience medication-resistant psychotic symptoms. The
cognitive-behaviorally based workbook is used to target improved self-management
of affective and psychotic symptoms. The intervention can be implemented
in community mental health settings by staff with less training than specialized
or licensed clinicians. Results show statistically significant improvement
on the Brief Psychiatric Rating Scale factor for Anxious Depression. This
is particularly relevant given the high levels of depression found among
individuals diagnosed with schizophrenia.
Keywords: cognitive-behavioral, hallucinations,
schizophrenia, self-help
IntroductionThis pilot
study explores a low-cost, mentored self-help intervention for auditory
hallucinations in a community mental health setting. The intervention
involves a mentor’s supportive assistance with written assignments exploring
individual voice-hearers’ experiences of auditory hallucinations (Coleman &
Smith, 1997; Hustig & Hafner, 1990). It focuses on assignments
operationalized in a published workbook, co-authored by a former psychiatric
patient and a psychiatric nurse (Coleman & Smith, 1997). Study
participants completed the workbook, rather than attending a specific number and
duration of treatment sessions. Participants were adults diagnosed with a
severe and persistent mood or psychotic disorder experiencing
medication-resistant psychotic symptoms. Results show statistically
significant improvement in the Brief Psychiatric Rating Scale (BPRS) factor
Anxious Depression for Intervention group participants, over those in the
Comparison group.
The “hearing voices movement” that began in Europe
following a 1987 conference in Utrecht (Romme & Escher, 1996) inspired
Coleman and Smith (1997) to challenge the view of “voices” as symptoms of an
illness unrelated to a person’s history. In their workbook, Coleman and
Smith also challenged the corollary that “voice hearers” are powerless
with regards to the voices. These authors noted that hearing voices is
“not the exclusive prerogative of saints and psychotics” (Coleman & Smith,
p. 8), but rather part of the human condition. Coleman and Smith provided
no specific goals for their workbook, but rather suggested that any action plan
a voice hearer develops should “be focused around your experiences and how you
understand them, and should work to your goals and nobody else’s [sic]”
(emphases in the original, p. 9).
Despite departures from
mainstream mental health/psychiatric thinking, seventeen of the twenty workbook
exercises share similarities with various techniques found in the cognitive
behavioral treatment (CBT) of psychosis. An established adjunctive
treatment approach in Europe and particularly the United Kingdom, CBT of
psychosis is increasingly recognized in North America (Dickerson, 2000;
Kinderman & Cooke, 2000). Overall, both Coleman and Smith’s (1997)
workbook and CBT of psychosis: (1) attempt to normalize the voice-hearing
experience, and (2) view hallucinations as on a continuum with normalcy.
Following Romme and Escher’s (1989, 1996) normalizing rationale, workbook
exercises begin with an exploration of the onset of voice hearing, and responses
to the voice hearing experience, then continue with the voice hearer’s written
“Life History” (Coleman & Smith, 1997, pp. 15-18).
Four of the 20
workbook exercises closely resemble “focusing” (Bentall, Haddock, & Slade
1994; Haddock, Bentall, & Slade, 1996). Focusing is a CBT of psychosis
strategy that examines the features, contents, related thoughts, and attributed
meaning(s) of “voices.” The workbook, for example, includes an “I’ve just
heard voices” checklist (Coleman & Smith, 1997, pp. 19-20) to photocopy and
use daily to describe the voices, voice content and surroundings, and the voice
hearer’s associated feelings and thoughts. This checklist also asks for
the voice hearer’s explanation of the voices. Subsequent workbook
exercises have the voice hearer address attributed meaning(s) of the voices
through identification of personal frames of reference, beliefs about the
voices, and an exploration of alternative belief systems. A difference
between the workbook’s orientation and CBT of psychosis is that the latter views
telepathy as a delusional or maladaptive explanation of voices that should be
challenged (e.g., Chadwick, Lowe, Horne, & Higson, 1994; Nelson,
1997). Workbook exercises, in contrast, neutrally explore alternative
belief systems (i.e., the illness model, the psychological model, and
telepathy).
Workbook exercises move on to emphasize coping with voices,
by using focusing and coping strategy enhancement (CSE) techniques, strategies
developed in CBT of psychosis (Tarrier et al., 1993; Yusupoff & Tarrier,
1996). Coping strategy exercises begin with an explanation of what “coping
strategy” means and examples of different types of coping strategies.
Exercises are meant to examine current strategies, changes desired (if any),
supports, and attributed meanings. Further exercises are meant to explore
alternative strategies and trials of new strategies. A total of thirteen
of twenty workbook exercises have similarities to CSE. The workbook frames
hearing voices as a potential adaptation to, or even survival strategy for, life
events. Guidance is provided to voice hearers for working with
professionals in this context. The net result for voice hearers interested
in working with their voices is an unusual combination of client driven,
non-judgmental exercises roughly similar in many respects to CBT intervention
strategies with psychosis.
At the time of this study’s inception,
empirical results from case study, single subject design, and small group
comparison study methodologies cautiously favored using CBT of psychosis with
clients experiencing various psychotic symptoms. Subsequent randomized
clinical trials (RCTs) have provided further support for individual CBT of
psychosis (Durham et al., 2003; Kuipers et al., 1998; NHS Centre for Reviews and
Dissemination, 2000; Rector & Beck, 2001; Sensky et al., 2000; Tarrier, et
al. 1999; Turkington, Kingdon & Turner, 2002). RCTs have utilized
multiple outcome measures, including measures of overall psychotic symptoms,
negative psychotic symptoms, depression, anxiety, self-esteem, self-concept and
other constructs. Generally, CBT of psychosis in the United Kingdom is
largely based on the work of Beck and colleagues, with overall agreement that
the principal aim “for medication-resistant psychosis is to reduce the distress
and interference with functioning caused by the psychotic symptoms” (Garety,
Fowler & Kuipers, 2000, p. 73). It is noteworthy that the outcome
measures used in CBT of psychosis intervention research do not directly measure
this intent, but rather measure symptom reduction, in addition to a plethora of
other variables.
Summarizing outcome results with psychotic
symptoms and adjunctive CBT of psychosis, Boyle (2002) stated that “although
some therapeutic results may be modest, most statistical comparisons with other
treatments, across a range of outcome measures, favour CBT” (p. 296).
Gaudiano (2005) tabulated 19 publications on 16 RCTs of CBT for psychosis that
included individual and group modalities, inpatient and outpatient samples,
first episode psychosis, recurrent psychosis, and older patients with
schizophrenia. Gaudiano cautiously concluded that “whether commonly used
therapies such as CBT are specifically efficacious in treating psychotic
symptoms” needs to be further researched, although evidence is clear that
psychosocial interventions generally can contribute “significantly to the
well-being of individuals suffering from psychosis beyond the effects of routine
care” (p. 46). Mueser and Noordsy (2005), following Gaudiano’s review,
nevertheless concluded that although “the mechanisms and specificity of CBT for
psychosis remain unknown, the evidence amassed supports its effectiveness” (p.
68).
Coleman and Smith’s (1997) workbook is intended for use with the
support of a trusted other (e.g., friend, significant other, family member,
and/or mental health professional), referred to in this study as a
“mentor.” With the workbook, power and authority are to reside solely with
the voice hearer, who sets the pace and may disengage with the supportive other
and/or discontinue the process without negative consequences at any point.
In addition, the voice hearer “owns” the workbook in a tangible, concrete way
seldom applicable to traditional therapy. This locus of control reflects
the self-help philosophy of the workbook.
It occurred to the present
authors that Coleman and Smith’s (1997) written guidelines might constitute an
additional repertoire of teachable coping strategies for psychotic symptoms in
typical mental health settings. Despite workbook similarities to
strategies found in formal individual CBT of psychosis, mentoring the workbook
requires less training and experience than is needed for CBT. Could an
intervention built around the workbook produce measurable positive changes in
self-esteem, social functioning, depressive and psychotic symptomatology, the
very areas that formal CBT of psychosis has explored? The present study
addressed this question.
MethodsThis study
utilized a non-equivalent comparison group design with non-random assignment to
evaluate pre-post intervention change in scores on standardized measures (see
below). The study was conducted in a south Florida community mental health
agency that serves adults diagnosed with severe and persistent mental
disorders. At the start of the study, the host agency served 480
“members.” Approximately 61% of agency members were male and 39% female,
51% Anglo and 49% Minority, with an age range from 18 to over 65. Agency
members had to report experiencing and/or display psychotic symptoms to meet
inclusion criteria (see below).
The sample was one of convenience,
based on staff referrals from the host agency. The Comparison group (n =
13) consisted of participants not scheduled to intervention protocol (n = 17)
after signing informed consent paperwork and completing pre-test packets.
Randomization was not possible, as participants were assigned to intervention
protocol based on their ability to meet initial scheduling windows
available. Over the course of the study, one participant suffered a stroke
and left the Intervention group and two Comparison group participants
discontinued services at the agency. Pre-test data from these three
non-completers are not included in the data set, since no corresponding
post-test data was obtained. Thus, data from the total of 27 participants
who completed the study are included in the analysis (Comparison group n =11,
Intervention group n = 16).
The sponsoring university’s Internal
Review Board and the host agency’s administration approved the study. The
primary researcher met individually with each person referred to the study in
order to explain the project and answer any questions about informed consent
documentation. Once informed consent was given, participants could
withdraw from the study at any time without penalty or reduction of agency
services.
MeasuresThe current study elected to measure
change in overall symptomatology, symptoms of depression and anxiety, and
self-esteem, using standardized instruments. These instruments have been
used in CBT of psychosis outcome studies in the United Kingdom (e.g., Haddock,
Bentall, & Slade, 1996; Kuipers et al., 1998; Tarrier et al., 1999), or in
community mental health research in the United States of America (Newman,
DeLiberty, McGrew, & Tejeda, 2005). Measures are discussed
below.
The Rosenberg Self-Esteem Scale (RSE, Fischer &
Corcoran, 1994; Rosenberg, 1989) is a self-report instrument used to measure
self-esteem. The RSE specifies a four-point scale used to self-rate ten
statements and was scored as a Likert scale. Possible scores range from a
low of 0 to a high of 30 (highest self-esteem). The instrument’s short
length and ease of administration made it suitable for inclusion in a pre and
post-intervention packet of multiple measures.
The Hoosier
Assurance Plan Inventory – Adult (HAPI-A) is a standardized, clinician-rated
psychosocial assessment instrument utilized by the state of Indiana with adults
diagnosed with severe and persistent mental disorders. The HAPI-A includes
the factor Symptoms of Distress and Mood (Factor 1, based upon three items, A –
Consumer’s Rating of Symptom Distress, B – Anxiety-Worrying, and C –
Depression-Sad, Blue, or Suicidal Thoughts/Actions), and the item Thought
Disorder, Item H. Item H reads: “Have you had any unusual
experiences (e.g., are there times you hear, see, or smell things other would
claim are not there)?” Two other HAPI-A factors can be used to measure
disruption in life (Factor 3 – Community Functioning, and Factor 4 – Social
Support-Skills & Housing). In the state of Indiana, the HAPI-A
demonstrated sensitivity to change for clients with psychiatric diagnoses, or
psychiatric diagnoses and chronic addiction, over a 90-day period HAPI-A
(Newman, DeLiberty, McGrew, & Tejeda, 2005).
For the HAPI-A, a
lower score indicates a more severe problem or symptom. Score range per
item on the HAPI-A is from seven to one. Since Factor 1 – Symptoms of
Distress and Mood is made up of three items, its score ranges from 21 to
three. Factor 3 – Community Functioning, and Factor 4 – Social
Support-Skills & Housing, are each comprised of four items, hence these
scores range from 28 to four. Item H (Thought Disorder) ranges from seven
to one and is reported separately.
The BPRS is a clinician-rated global
instrument for measuring symptoms of psychopathology that includes items related
to depression and anxiety (Faustman & Overall, 1999; Overall & Gorham,
1962). Overall and Klett (1972) identified four general factors within the
BPRS, including the factor Anxious Depression. This factor is based upon
three subscales, i.e., Anxiety, Guilt Feelings, and Depressed Mood. The
BPRS measures clinical symptoms across a range of mental diagnoses, such as
those present in the clinical sample studied. Possible BPRS global scores
for overall symptomatology range from 18 to 126, where 18 indicates no symptoms
and 126 indicates all symptoms rate as extremely severe. The higher the
BPRS global or factor score, the more severe is the symptom rating.
Inclusion CriteriaStudy data collection began in the fall
of 2001 and extended into the winter of 2004. Given a sample of
convenience, non-random assignment to group, and non-equivalent groups, results
should not be generalized to the larger population of Americans diagnosed with
major mental disorders and experiencing psychotic symptoms who reside in the
community. Study inclusion criteria included agency membership; this
excluded developmentally delayed or mentally retarded individuals, as well as
individuals using alcohol or illicit substances.
Additional inclusion
criteria were as follows: (1) 21 to 65 years of age; (2) no legal
guardian; (3) English literacy/fluency; (4) agency record of a DSM-IV (American
Psychiatric Association, 1994) diagnosis of Schizophrenia, Schizoaffective
Disorder, or Mood Disorder with psychotic features; if the disorder on record
was none of these and criterion six (below) was met, intervention protocol was
deemed potentially appropriate and the agency member was permitted to enroll in
the study (n = 1); (5) agency record of a DSM-IV Global Assessment of
Functioning (Axis V) score in the range of 35 to 60; (6) reports by agency staff
of observable symptoms such as delusional verbalization or aberrant behavior,
and/or verbalization of a problem related to auditory hallucinations, “voices,”
intrusive thoughts, or excessive doubts or worries, despite reported adherence
to prescribed psychotropic medication; (7) community residence (defined to
include residential treatment facilities, assisted living facilities, and group
homes); and (8) either no alcohol or illegal substance use diagnoses, or no
current alcohol or illegal substance use per staff and self-report, if such
diagnoses were on record at the agency.
The first author extracted data
on participant demographic and clinical characteristics from agency case
files. MSW-level social workers not affiliated with the host agency and
blind to intervention/comparison group status administered pre and post-test
instruments. Weekly intervention sessions with each participant began
after completion of the pre-test packet, with the host agency requirement that
the first author act as mentor. Broad variation in both number of sessions
and duration of the intervention was expected and, indeed, occurred (range from
12 to 42 weeks, with one outlier at 57 weeks; details below).
A mentored
session with an Intervention group participant began with the Topography of
Voices Rating Scale (TVRS). The TVRS is a one-page, unstandardized
self-report instrument (Chadwick, Birchwood & Trower, 1996; Hustig &
Hafner, 1990) used as an “ice-breaker” to support open discussion of
symptoms. Sessions were one-on-one and followed a semi-structured format
of 15 to 45 minute duration. (The mentor documented details of each
session on the Mentor Report Form.) After completing the TVRS and
responding to initial inquiries on medication and current status, the
participant was handed the workbook. Each workbook exercise was read aloud
and any confusion clarified prior to the participant completing it. Verbal
responses were redirected with a gentle “write it down.” Once the workbook
was completed, the mentor facilitated contact between participant and assessor
to schedule the post-test. As a participant completed intervention
protocol, the mentor referred both that participant and a Comparison group
participant to an assessor for post-testing (this was not possible for five
Intervention group participants, because of differing group
sizes).
Research Questions and Data AnalysisThis study
aims to determine if a low cost mentored intervention that uses Coleman and
Smith’s (1997) workbook provides benefits to clients experiencing psychotic
symptoms beyond what treatment as usual provides. This aim is reflected in
the following four research questions: (1) does self-esteem increase
post-intervention, relative to self-esteem of a comparison group not receiving
the intervention?; (2) does depression-anxiety decrease post-intervention,
relative to a comparison group?; (3) does overall psychotic symptomatology
decrease post-intervention, relative to a comparison group?; and (4) does
disruption in life lessen post-intervention, relative to a comparison
group?.
Repeated measures analysis of variance (Repeated measures
ANOVA, or RMANOVA) assessed whether positive change occurred over: (1)
self-esteem, (2) depression-anxiety, (3) overall psychotic symptomatology, and
(4) disruption in life. Two measures were used for the latter three of the
four constructs, and Bonferroni corrections set Type I (p) error at .025 (i.e.,
.05/2) for these analyses. The general linear model (GLM) approach within
the Statistical Package for Social Sciences (SPSS) Version 11.0 was used to
conduct the analysis.
ANOVA is relatively robust regarding failures to
meet assumptions of homogeneity and normality (Garson, 2005). The F-test
(or F-ratio) is the key statistic for ANOVA and its formula reflects whether the
variance among the group means (for given sample size and within group
variances) is significantly larger than the error variance within the
groups. With smaller variances and smaller samples, F is conservative,
i.e., it is more difficult to detect statistical significance (Garson,
2005). When using the GLM model within SPSS, the F-test is unaffected by
unequal group sizes. In studies evaluating cognitive-behavioral or other
individual psychotherapy approaches, large samples of individuals diagnosed with
serious mental disorders are seldom available (Gottdiener & Haslam,
2002). Researchers have used any one of several effect size statistics to
describe the magnitude of any significant differences observed between
intervention conditions. In this study, effect size was estimated using
the “partial eta square” statistic, which reflects the proportion of variance
associated with a given
variable.
ResultsSpecific
demographic and clinical characteristics of Intervention and Comparison group
participants are shown in Table 1. Overall, Intervention group
participants tended to be: (1) an average of seven years older, (2) more likely
to have more debilitating psychiatric disorder diagnoses, and (3) more likely to
be of non-Hispanic White ethnicity/race, than Comparison group members.
<>Table 1
Intervention and Comparison Group Demographics (n =
27)
|
|
Intervention
Group
(n = 16) |
Comparison
Group
(n =
11) |
|
Characteristic |
n
(%) |
n
(%) |
|
Gender |
|
|
|
Female |
4 (25) |
3
(27) |
|
|
12 (75) |
8
(73) |
|
Race/Ethnicity |
|
|
|
White |
13 (81) |
7
(64) |
|
Minority |
3 (19) |
4
(36) |
|
Marital Status |
|
|
|
Single/Divorced |
15 (94) |
10
(91) |
|
Married |
1 (6) |
1 (9) |
|
Education |
|
|
|
High School or below |
7 (44) |
6
(55) |
|
Post High School/GED |
9 (56) |
5
(45) |
|
Residence |
|
|
|
Independent |
11 (69) |
7
(64) |
|
Group home
Diagnostic Category |
5 (31) |
4
(36) |
|
|
15(94) |
7(64) |
|
Mood Disorder |
1(6) |
3(27) |
|
|
0(0) |
1(9) |
Table 2 shows that at
pre-test, the Intervention group had significantly higher BPRS global
scores. However, the difference on the BPRS Anxious Depression factor was
not statistically significant and other differences appeared trivial and were
not statistically significant.
This pilot study employs a
quasi-experimental pre-post design (n = 27) to evaluate the impact of a mentored
self-help workbook (Coleman & Smith, 1997) intervention.
<>Table 2
Between Group Differences at Pre-test
|
Measure |
Group
(I = 16, C = 11) |
Mean + SD |
Range |
F
(dF: 1, 25) |
p |
Partial
Eta Squared |
|
RSE |
Inter. |
19.31 + 6.26 |
8-30 |
0.613
|
|
.024 |
|
|
Comp. |
21.09 + 5.03 |
14-30 |
|
BPRS Anx.Dep. |
Inter. |
8.06 + 3.13 |
3-13 |
3.428
(1,24) |
.076 |
.125 |
|
|
Comp.
(10) |
5.80 + 2.86 |
2-13 |
|
HAPI-A Mood |
Inter. |
15.94 + 4.19 |
9-21 |
.146
|
.706 |
.006 |
|
|
Comp. |
16.55 + 3.82 |
6-21 |
|
BPRS Global |
Inter. |
37.56 + 7.79 |
25-50 |
5.729
(1,24) |
.025 |
.193 |
|
|
Comp.
(10) |
29.60 + 8.97 |
19-43 |
|
HAPI-A Tht.Dis. |
Inter. |
4.88 + 2.03 |
1-7 |
1.552
|
.224 |
.058 |
|
|
Comp. |
5.82 + 1.78 |
1-7 |
|
HAPI-A Comm. |
Inter. |
20.56 + 5.14 |
11-28 |
.439
|
.514 |
.017 |
|
|
Comp. |
21.82 + 4.35 |
14-28 |
|
HAPI-A Soc.Supp. |
Inter. |
23.69 + 4.01 |
11-28 |
.001
|
.982 |
<.001 |
|
|
Comp. |
23.73 + 5.02 |
14-28 |
The number of mentored
self-help sessions for 15 Intervention group participants ranged from eight to
18 (mean = 12.6) with a duration range of 12 to 42 weeks (mean = 28.3),
excluding the one participant with 25 sessions over 57 weeks. In sum,
there was a pronounced central tendency of 13 sessions over a 29-week period,
despite differing levels of education/literacy and scheduling
idiosyncracies. As noted above, the intervention aimed only for workbook
completion (a behavioral criteria) rather than for a specific “dosage” of
intervention, thus neither the duration of the intervention nor the number of
sessions should be taken as an indicator of quantity or intensity: Longer
duration indicated slower progress in completing workbook
exercises.
Pre-post differences analyzed using RMANOVA are shown in Table
3. Using RMANOVA and appropriate Bonferroni corrections, no significant
differences were found for self-esteem, overall psychotic symptoms, or
disruption in life. For depression and anxiety, the two measures used were
the BPRS Anxious Depression and HAPI-A Distress-Mood factors. Because the
statistical test required two separate analyses, a Bonferroni correction set
Type I error (p) at .025 (i.e., .05/2). No significant difference was
found between groups for the HAPI-A factor, however, a significant difference
was found between groups for the BPRS factor, with a strong effect size, η2 =
.218. Further, the correlation between the change in scores for the BPRS
factor Anxious Depression and the change in scores for the HAPI-A Factor
Symptoms of Distress and Mood was significant at the .05 level (r =
-.341). In sum, one of two measures of depression-anxiety symptoms
suggested that these symptoms showed significantly greater reduction for the
Intervention group and the two measures were significantly correlated with each
other.
<>Table 3
Pre-post Test Differences:
ANOVA Results
|
Measure |
Group
(I = 16, C =
11) |
Mean +
SD |
Range |
F
(dF: 1,
25) |
p |
Partial Eta
Squared |
|
RSE |
Inter. |
18.81 +
4.17 |
10-26 |
0.006
|
|
<.001 |
|
|
Comp. |
20.73 +
4.27 |
16-30 |
|
BPRS Anx.Dep. |
Inter. |
6.69 +
3.24 |
3-13 |
6.985
(1, 24) |
.014 |
.218 |
|
|
Comp.
(10) |
7.70 +
3.89 |
1-15 |
|
HAPI-A Mood |
Inter. |
15.31 +
4.50 |
8-21 |
.193
|
.664 |
.008 |
|
|
Comp. |
16.73 +
3.04 |
11-21 |
|
BPRS Global |
Inter. |
37.94 +
12.0 |
18-65 |
.577
(1, 24) |
.455 |
.023 |
|
|
Comp.
(10) |
34.70 +
10.8 |
23-51 |
|
HAPI-A Tht.Dis. |
Inter. |
5.25 +
1.77 |
2-7 |
.016
|
.902 |
.001 |
|
|
Comp. |
6.09 +
1.14 |
3-7 |
|
HAPI-A Comm. |
Inter. |
22.19 +
3.60 |
14-27 |
.067
|
.797 |
.003 |
|
|
Comp. |
23.82 +
3.09 |
16-28 |
|
HAPI-A Soc.Supp. |
Inter. |
23.13 +
4.84
24.64 +
3.07 |
14-28
17-28 |
.707
|
.408 |
.028 |
|
|
Comp. |
DiscussionThe
study used three standardized instruments with an Intervention and a
treatment-as-usual Comparison group, to examine pre-post differences over four
constructs. Research questions related to self-esteem, depression-anxiety,
overall psychotic symptomatology, and disruption-in-life, respectively.
Interestingly, five of seven outcomes showed non-significant change scores that
favored the Comparison group over the Intervention group. These outcomes
do not reach statistical significance, and whether they would sustain with a
more powerful study is a question for future research.
The study is an
exploratory pilot and findings are limited. Results cannot be generalized,
given the small sample size, non-random assignment to group, non-equivalent
groups, and other study limitations (see recommendations below). Overall,
a conservative interpretation of results is that the one significant difference
in pre-post instrument scores occurred due to chance. An alternative
interpretation is that the mentored self-help intervention made an actual
improvement in the level of depression-anxiety experienced by Intervention group
participants. This is particularly relevant, if so, given the high levels
of depression and depression-associated suicide among individuals diagnosed with
schizophrenia. The alternative interpretation supports further research on
the intervention.
Recommendations for a future study address
limitations of the current one and include: (1) random assignment to
group; (2) use of different mentors simultaneously, each mentor working
one-on-one with individual participants, to avoid the confound of a single
individual administering the intervention; (3) advance stipulation of the number
of sessions to standardize “dosage;” (4) use of specific standardized
instruments to assess symptoms of depression and anxiety; (5) use of a
standardized measure of self-efficacy rather than self-esteem; and possibly (6)
use of qualitative measures, rather than the HAPI-A, to assess disruption in
life.
The statistically significant result obtained was over the
construct depression-anxiety and one might cautiously conclude that the single
pre-post difference was an artifact of multiple measures over multiple
questions, i.e., that one of seven measures (14%) showed improvement purely due
to chance, despite a priori formulation of research questions and an appropriate
use of Bonferroni corrections in the analysis. The change in the more
disturbed Intervention group might also indicate regression towards a mean; if
so, however, one might have expected the global score of the same scale to show
a similar shift and this did not occur. The BPRS Anxious Depression factor
pre-post difference showed a strong effect size, and although the difference was
only seen with one of two measures, the difference scores on both the BPRS and
the HAPI-A factors correlated significantly at the .05 level. A more
positive interpretation of observed results is that the intervention served to
assist individuals with severe and persistent psychotic symptoms in reducing
distress associated with at least some of those symptoms.
Few CBT studies
have measured secondary aspects of psychosis such as depressive symptoms or
anxiety, although Sensky et al. (2000) and Turkington, Kingdon and Turner (2002)
reported improvements in depressive symptoms. Rector and Beck (2001) noted
“upwards of two-thirds of patients receiving a diagnosis of schizophrenia will
also experience a major depressive episode” (p. 285). Kaplan and Sadock
(1998) reported up to ten percent of people diagnosed with schizophrenia die
from suicide and that an estimated 4,000 people diagnosed with schizophrenia in
the United States die annually by suicide (see also World Health Report,
2001). Further, only a small percentage of these people commit suicide
because of psychotic symptoms: depressive symptoms are associated with over
two-thirds of these suicides. Beck (in Kingdon & Turkington, 1994)
correctly highlighted depressive symptoms as natural sequelae of a schizophrenic
diagnosis. If the mentored self-help workbook intervention is shown in
future studies to decrease levels of depression in this population, the
intervention format lends itself to implementation in community mental health
agency settings through supportive staff.
An excursion into speculative
thought is in order, given (1) the observed reduction in BPRS Anxious Depression
scores for the Intervention group, (2) the positive impact of all major forms of
individual therapy for those diagnosed with schizophrenia (Gottdiener &
Haslam, 2002), and (3) the prevalence of depressive symptoms and suicide in this
population. Given the demonstrated positive impact of all forms of
individual therapy, depressive symptoms and associated suicides might be reduced
by use of interpersonal, relational interventions. The implication for
practice with this population is that developing interpersonal
practitioner-client relationships based on mutual respect, trust, and client
choice is a critical foundation of treatment. Use of a self-help workbook
co-authored by a mental health consumer might assist the development of such
practitioner-client relationships, whether the workbook was used one-on-one or
within a group format. Study results indicate that the workbook – despite
its departures from mainstream mental health thinking – when used one-on-one
with a supportive mentor, appeared to do no harm and that it may in fact be a
positive process for clients experiencing medication resistant psychotic
symptoms.